TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer

BACKGROUND: Muscle-invasive bladder cancer (MIBC) is an aggressive neoplasm with poor prognosis, lacking effective therapeutic targets. Oncogenic dependency on members of the TAM tyrosine kinase receptor family (TYRO3, AXL, MERTK) has been reported in several cancer types, but their role in bladder...

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Detalles Bibliográficos
Autores principales: Dufour, Florent, Silina, Linda, Neyret-Kahn, Hélène, Moreno-Vega, Aura, Krucker, Clémentine, Karboul, Narjesse, Dorland-Galliot, Marion, Maillé, Pascale, Chapeaublanc, Elodie, Allory, Yves, Stransky, Nicolas, Haegel, Hélène, Menguy, Thierry, Duong, Vanessa, Radvanyi, François, Bernard-Pierrot, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461973/
https://www.ncbi.nlm.nih.gov/pubmed/30765874
http://dx.doi.org/10.1038/s41416-019-0397-6

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