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Serotonin transporter inhibition and 5-HT(2C) receptor activation drive loss of cocaine-induced locomotor activation in DAT Val559 mice

Dopamine (DA) signaling dysfunction is believed to contribute to multiple neuropsychiatric disorders including attention-deficit/hyperactivity disorder (ADHD). The rare DA transporter (DAT) coding substitution Ala559Val found in subjects with ADHD, bipolar disorder and autism, promotes anomalous DA...

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Detalles Bibliográficos
Autores principales:	Stewart, Adele, Davis, Gwynne L., Gresch, Paul J., Katamish, Rania M., Peart, Rodeania, Rabil, Maximilian J., Gowrishankar, Raajaram, Carroll, F. Ivy, Hahn, Maureen K., Blakely, Randy D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462012/ https://www.ncbi.nlm.nih.gov/pubmed/30578419 http://dx.doi.org/10.1038/s41386-018-0301-8

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