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Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected human macrophages
Long noncoding RNAs (lncRNAs) impart significant regulatory functions in a diverse array of biological pathways and manipulation of these RNAs provides an important avenue to modulate such pathways, particularly in disease. Our knowledge about lncRNAs’ role in determination of cellular fate during H...
Autores principales: | Boliar, Saikat, Gludish, David W., Jambo, Kondwani C., Kamng’ona, Raphael, Mvaya, Leonard, Mwandumba, Henry C., Russell, David G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462110/ https://www.ncbi.nlm.nih.gov/pubmed/30918127 http://dx.doi.org/10.1073/pnas.1818662116 |
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