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A CRISPR/Cas9-based central processing unit to program complex logic computation in human cells
Controlling gene expression with sophisticated logic gates has been and remains one of the central aims of synthetic biology. However, conventional implementations of biocomputers use central processing units (CPUs) assembled from multiple protein-based gene switches, limiting the programming flexib...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462112/ https://www.ncbi.nlm.nih.gov/pubmed/30923122 http://dx.doi.org/10.1073/pnas.1821740116 |