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The Human Lung Mucosa Drives Differential Mycobacterium tuberculosis Infection Outcome in the Alveolar Epithelium

Mycobacterium tuberculosis (M.tb) is deposited into the alveolus where it first encounters the alveolar lining fluid (ALF) prior contacts host cells. We demonstrated that M.tb-exposure to human ALF alters its cell surface, driving better M.tb infection control by professional phagocytes. Contrary to...

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Detalles Bibliográficos
Autores principales: Scordo, JM, Olmo-Fontánez, AM, Kelley, HV, Sidiki, S, Arcos, J, Akhter, A, Wewers, MD, Torrelles, JB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462240/
https://www.ncbi.nlm.nih.gov/pubmed/30846830
http://dx.doi.org/10.1038/s41385-019-0156-2