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The Human Lung Mucosa Drives Differential Mycobacterium tuberculosis Infection Outcome in the Alveolar Epithelium
Mycobacterium tuberculosis (M.tb) is deposited into the alveolus where it first encounters the alveolar lining fluid (ALF) prior contacts host cells. We demonstrated that M.tb-exposure to human ALF alters its cell surface, driving better M.tb infection control by professional phagocytes. Contrary to...
Autores principales: | Scordo, JM, Olmo-Fontánez, AM, Kelley, HV, Sidiki, S, Arcos, J, Akhter, A, Wewers, MD, Torrelles, JB |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462240/ https://www.ncbi.nlm.nih.gov/pubmed/30846830 http://dx.doi.org/10.1038/s41385-019-0156-2 |
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