Selective delipidation of Mycobacterium bovis BCG enables direct pulmonary vaccination and enhances protection against Mycobacterium tuberculosis

Mycobacterium tuberculosis (M.tb), the causative agent of tuberculosis (TB), is the leading killer due to an infectious organism. Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only vaccine approved against TB, however, its efficacy against pulmonary TB is poor. While BCG is currently ino...

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Detalles Bibliográficos
Autores principales: Moliva, Juan I., Hossfeld, Austin P., Sidiki, Sabeen, Canan, Cynthia H., Dwivedi, Varun, Beamer, Gillian, Turner, Joanne, Torrelles, Jordi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462255/
https://www.ncbi.nlm.nih.gov/pubmed/30778118
http://dx.doi.org/10.1038/s41385-019-0148-2

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