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Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants

Detalles Bibliográficos
Autores principales: Xin, Huhu, Wan, Tao, Ping, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462278/
https://www.ncbi.nlm.nih.gov/pubmed/30993016
http://dx.doi.org/10.1038/s41392-019-0044-y
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author Xin, Huhu
Wan, Tao
Ping, Yuan
author_facet Xin, Huhu
Wan, Tao
Ping, Yuan
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spelling pubmed-64622782019-04-16 Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants Xin, Huhu Wan, Tao Ping, Yuan Signal Transduct Target Ther Research Highlight Nature Publishing Group UK 2019-04-12 /pmc/articles/PMC6462278/ /pubmed/30993016 http://dx.doi.org/10.1038/s41392-019-0044-y Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Highlight
Xin, Huhu
Wan, Tao
Ping, Yuan
Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants
title Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants
title_full Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants
title_fullStr Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants
title_full_unstemmed Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants
title_short Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants
title_sort off-targeting of base editors: be3 but not abe induces substantial off-target single nucleotide variants
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462278/
https://www.ncbi.nlm.nih.gov/pubmed/30993016
http://dx.doi.org/10.1038/s41392-019-0044-y
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