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Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462278/ https://www.ncbi.nlm.nih.gov/pubmed/30993016 http://dx.doi.org/10.1038/s41392-019-0044-y |
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author | Xin, Huhu Wan, Tao Ping, Yuan |
author_facet | Xin, Huhu Wan, Tao Ping, Yuan |
author_sort | Xin, Huhu |
collection | PubMed |
description | |
format | Online Article Text |
id | pubmed-6462278 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-64622782019-04-16 Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants Xin, Huhu Wan, Tao Ping, Yuan Signal Transduct Target Ther Research Highlight Nature Publishing Group UK 2019-04-12 /pmc/articles/PMC6462278/ /pubmed/30993016 http://dx.doi.org/10.1038/s41392-019-0044-y Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Highlight Xin, Huhu Wan, Tao Ping, Yuan Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants |
title | Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants |
title_full | Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants |
title_fullStr | Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants |
title_full_unstemmed | Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants |
title_short | Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants |
title_sort | off-targeting of base editors: be3 but not abe induces substantial off-target single nucleotide variants |
topic | Research Highlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462278/ https://www.ncbi.nlm.nih.gov/pubmed/30993016 http://dx.doi.org/10.1038/s41392-019-0044-y |
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