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Enhancement of Expression Level of Modified t-PA (TNKase) in Leishmania tarentolae by Induction System
BACKGROUND: The expression of bio-therapeutic proteins in mammalian cells, such as CHO, attains high homogeneity related to post-translational modifications. Although CHO remains the most popular cell line for bestselling biotherapeutic proteins on the market, there are still drawbacks such as expen...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pasteur Institute
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462294/ https://www.ncbi.nlm.nih.gov/pubmed/30220189 http://dx.doi.org/10.29252/.23.4.272 |