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Fournier’s gangrene: prospective study of 34 patients in South Indian population and treatment strategies

INTRODUCTION: Fournier's gangrene (FG) is a fulminant necrotizing fasciitis of the perineum and genitalia. The objective of this study was to study the etiology and microbiology associated with FG and to study the debridement and reconstructive procedures required in these patients. METHODS: Th...

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Autores principales: Sockkalingam, Vigneswara Srinivasan, Subburayan, Elankumar, Velu, Elango, Rajashekar, Sujith Tumkur, Swamy, Anusha Mruthyunjaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462357/
https://www.ncbi.nlm.nih.gov/pubmed/31037161
http://dx.doi.org/10.11604/pamj.2018.31.110.15495
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author Sockkalingam, Vigneswara Srinivasan
Subburayan, Elankumar
Velu, Elango
Rajashekar, Sujith Tumkur
Swamy, Anusha Mruthyunjaya
author_facet Sockkalingam, Vigneswara Srinivasan
Subburayan, Elankumar
Velu, Elango
Rajashekar, Sujith Tumkur
Swamy, Anusha Mruthyunjaya
author_sort Sockkalingam, Vigneswara Srinivasan
collection PubMed
description INTRODUCTION: Fournier's gangrene (FG) is a fulminant necrotizing fasciitis of the perineum and genitalia. The objective of this study was to study the etiology and microbiology associated with FG and to study the debridement and reconstructive procedures required in these patients. METHODS: This was a prospective follow up study conducted from September 2011 to November 2012 at Coimbatore medical college hospital, Coimbatore, India. Patients presenting to the outpatient department and emergency department with the clinical diagnosis of FG were included in the study. RESULTS: A total of 34 patients were studied in the study period. The mean age of presentation in years was 50±11.13. The male to female ratio was 33:1. The source of the infection was most commonly anorectal. Diabetes mellitus was the most common co morbid factor associated. Most commonly the disease was polymicrobial with escherichia coli being the commonest grown organism. The average number of wound debridement required was 2.9±1.42. Primary closure of the scrotal skin defect was the most common reconstructive procedure performed. Mortality associated with the disease in our series was 11.8%. CONCLUSION: Although FG is a relatively rare disease, it is still prevalent in Indian population. Incidence of FG in HIV patients is high, even though it is not the commonest of the co morbid condition. The mortality can be kept to minimal with aggressive medical and surgical management. Extensive raw area following the infection and wound debridement can be managed by simple reconstructive procedures with good outcome.
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spelling pubmed-64623572019-04-29 Fournier’s gangrene: prospective study of 34 patients in South Indian population and treatment strategies Sockkalingam, Vigneswara Srinivasan Subburayan, Elankumar Velu, Elango Rajashekar, Sujith Tumkur Swamy, Anusha Mruthyunjaya Pan Afr Med J Research INTRODUCTION: Fournier's gangrene (FG) is a fulminant necrotizing fasciitis of the perineum and genitalia. The objective of this study was to study the etiology and microbiology associated with FG and to study the debridement and reconstructive procedures required in these patients. METHODS: This was a prospective follow up study conducted from September 2011 to November 2012 at Coimbatore medical college hospital, Coimbatore, India. Patients presenting to the outpatient department and emergency department with the clinical diagnosis of FG were included in the study. RESULTS: A total of 34 patients were studied in the study period. The mean age of presentation in years was 50±11.13. The male to female ratio was 33:1. The source of the infection was most commonly anorectal. Diabetes mellitus was the most common co morbid factor associated. Most commonly the disease was polymicrobial with escherichia coli being the commonest grown organism. The average number of wound debridement required was 2.9±1.42. Primary closure of the scrotal skin defect was the most common reconstructive procedure performed. Mortality associated with the disease in our series was 11.8%. CONCLUSION: Although FG is a relatively rare disease, it is still prevalent in Indian population. Incidence of FG in HIV patients is high, even though it is not the commonest of the co morbid condition. The mortality can be kept to minimal with aggressive medical and surgical management. Extensive raw area following the infection and wound debridement can be managed by simple reconstructive procedures with good outcome. The African Field Epidemiology Network 2018-10-12 /pmc/articles/PMC6462357/ /pubmed/31037161 http://dx.doi.org/10.11604/pamj.2018.31.110.15495 Text en © Vigneswara Srinivasan Sockkalingam et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Sockkalingam, Vigneswara Srinivasan
Subburayan, Elankumar
Velu, Elango
Rajashekar, Sujith Tumkur
Swamy, Anusha Mruthyunjaya
Fournier’s gangrene: prospective study of 34 patients in South Indian population and treatment strategies
title Fournier’s gangrene: prospective study of 34 patients in South Indian population and treatment strategies
title_full Fournier’s gangrene: prospective study of 34 patients in South Indian population and treatment strategies
title_fullStr Fournier’s gangrene: prospective study of 34 patients in South Indian population and treatment strategies
title_full_unstemmed Fournier’s gangrene: prospective study of 34 patients in South Indian population and treatment strategies
title_short Fournier’s gangrene: prospective study of 34 patients in South Indian population and treatment strategies
title_sort fournier’s gangrene: prospective study of 34 patients in south indian population and treatment strategies
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462357/
https://www.ncbi.nlm.nih.gov/pubmed/31037161
http://dx.doi.org/10.11604/pamj.2018.31.110.15495
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