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How to maintain the maximal level of blinding in randomisation for a placebo-controlled drug trial
We illustrate the approach of randomising treatments and compare it with the traditional approach of randomising patients, using a case study drawn from the authors’ experience in clinical trials. The setting is a double-blind parallel two-arm randomised controlled trial (RCT), but the method in thi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462539/ https://www.ncbi.nlm.nih.gov/pubmed/31011659 http://dx.doi.org/10.1016/j.conctc.2019.100356 |