Adenovirus‐associated antibodies in UK cohort of hemophilia patients: A seroprevalence study of the presence of adenovirus‐associated virus vector–serotypes AAV5 and AAV8 neutralizing activity and antibodies in patients with hemophilia A

BACKGROUND: Current treatment for severe hemophilia A is replacement of deficient factor. Although replacement therapy has improved life expectancy and quality, limitations include frequent infusions and high costs. Gene therapy is a potential alternative that utilizes an adeno‐associated virus (AAV...

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Detalles Bibliográficos
Autores principales: Stanford, Sophia, Pink, Ruth, Creagh, Desmond, Clark, Amanda, Lowe, Gillian, Curry, Nicola, Pasi, John, Perry, David, Fong, Sylvia, Hayes, Gregory, Chandrakumaran, Kandiah, Rangarajan, Savita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles: Haemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462753/
https://www.ncbi.nlm.nih.gov/pubmed/31011710
http://dx.doi.org/10.1002/rth2.12177

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