Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency

Lysine (K) type cationic lipid with a propyl spacer and ditetradecyl hydrophobic moieties composing liposomes, K3C14, previously studied for gene delivery, were reported to activate the NLRP3 inflammasomes in human macrophages via the conventional phagolysosomal pathway. In this study, K3C16, a prop...

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Detalles Bibliográficos
Autores principales: He, Jieyan, Li, Tianshu, Próchnicki, Tomasz, Horvath, Gabor, Latz, Eicke, Takeoka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462779/
https://www.ncbi.nlm.nih.gov/pubmed/31011633
http://dx.doi.org/10.1016/j.bbrep.2019.100623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462779/
https://www.ncbi.nlm.nih.gov/pubmed/31011633
http://dx.doi.org/10.1016/j.bbrep.2019.100623

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