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C-terminal α Domain of p63 Binds to p300 to Coactivate β-Catenin

TP63 (p63), a member of the tumor suppressor TP53 (p53) gene family, is essential for ectodermal tissue development and suppresses malignant progression of carcinomas. The most abundant isoform, ΔNp63α (referred to as p63), lacks the N-terminal transactivation (TA) domain, and was originally charact...

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Detalles Bibliográficos
Autores principales: Katoh, Iyoko, Maehata, Yojiro, Moriishi, Kohji, Hata, Ryu-Ichiro, Kurata, Shun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462804/
https://www.ncbi.nlm.nih.gov/pubmed/30986748
http://dx.doi.org/10.1016/j.neo.2019.03.010