Cargando…

In Systemic Sclerosis, a Unique Long Non Coding RNA Regulates Genes and Pathways Involved in the Three Main Features of the Disease (Vasculopathy, Fibrosis and Autoimmunity) and in Carcinogenesis

Systemic sclerosis (SSc) is an autoimmune disease characterized by three main features: vasculopathy, immune system dysregulation and fibrosis. Long non-coding RNAs (lncRNAs) may play a role in the pathogenesis of autoimmune diseases and a comprehensive analysis of lncRNAs expression in SSc is still...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dolcino, Marzia, Tinazzi, Elisa, Puccetti, Antonio, Lunardi, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462909/ https://www.ncbi.nlm.nih.gov/pubmed/30866419 http://dx.doi.org/10.3390/jcm8030320

Ejemplares similares

Gene Expression Profiling in Fibromyalgia Indicates an Autoimmune Origin of the Disease and Opens New Avenues for Targeted Therapy
por: Dolcino, Marzia, et al.
Publicado: (2020)

Long Non-Coding RNAs Target Pathogenetically Relevant Genes and Pathways in Rheumatoid Arthritis
por: Dolcino, Marzia, et al.
Publicado: (2019)

Long Non-Coding RNAs Modulate Sjögren’s Syndrome Associated Gene Expression and Are Involved in the Pathogenesis of the Disease
por: Dolcino, Marzia, et al.
Publicado: (2019)

Gene Profiling in Patients with Systemic Sclerosis Reveals the Presence of Oncogenic Gene Signatures
por: Dolcino, Marzia, et al.
Publicado: (2018)

Long Non-Coding RNAs Play a Role in the Pathogenesis of Psoriatic Arthritis by Regulating MicroRNAs and Genes Involved in Inflammation and Metabolic Syndrome
por: Dolcino, Marzia, et al.
Publicado: (2018)

Crossreactive Autoantibodies Directed against Cutaneous and Joint Antigens Are Present in Psoriatic Arthritis
por: Dolcino, Marzia, et al.
Publicado: (2014)

Gene expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified by iloprost infusion
por: Tinazzi, Elisa, et al.
Publicado: (2010)

Gene Expression Profiling in Behcet's Disease Indicates an Autoimmune Component in the Pathogenesis of the Disease and Opens New Avenues for Targeted Therapy
por: Puccetti, Antonio, et al.
Publicado: (2018)

Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis
por: Elisa, Tinazzi, et al.
Publicado: (2015)

Gene Expression Analysis before and after Treatment with Adalimumab in Patients with Ankylosing Spondylitis Identifies Molecular Pathways Associated with Response to Therapy
por: Dolcino, Marzia, et al.
Publicado: (2017)

Antibodies Directed against a Peptide Epitope of a Klebsiella pneumoniae-Derived Protein Are Present in Ankylosing Spondylitis
por: Puccetti, Antonio, et al.
Publicado: (2017)

Gene Expression Profiling in Peripheral Blood Cells and Synovial Membranes of Patients with Psoriatic Arthritis
por: Dolcino, Marzia, et al.
Publicado: (2015)

MicroRNA Expression Profiling in Psoriatic Arthritis
por: Pelosi, Andrea, et al.
Publicado: (2018)

Endothelial Cells' Activation and Apoptosis Induced by a Subset of Antibodies against Human Cytomegalovirus: Relevance to the Pathogenesis of Atherosclerosis
por: Lunardi, Claudio, et al.
Publicado: (2007)

Gene Expression Profiling in Peripheral Blood Mononuclear Cells of Patients with Common Variable Immunodeficiency: Modulation of Adaptive Immune Response following Intravenous Immunoglobulin Therapy
por: Dolcino, Marzia, et al.
Publicado: (2014)

Characterization of CD30/CD30L(+) Cells in Peripheral Blood and Synovial Fluid of Patients with Rheumatoid Arthritis
por: Barbieri, Alessandro, et al.
Publicado: (2015)

Editorial: Role of Epigenetics in Autoimmune Diseases
por: Dolcino, Marzia, et al.
Publicado: (2020)

Antibodies against Human Cytomegalovirus in the Pathogenesis of Systemic Sclerosis: A Gene Array Approach
por: Lunardi, Claudio, et al.
Publicado: (2006)

Gene Expression Profiling in Dermatitis Herpetiformis Skin Lesions
por: Dolcino, M., et al.
Publicado: (2012)

The Pathogenesis of Systemic Sclerosis: The Origin of Fibrosis and Interlink with Vasculopathy and Autoimmunity
por: Ko, Junsuk, et al.
Publicado: (2023)

MicroRNA Expression Profiling in Behçet's Disease
por: Puccetti, Antonio, et al.
Publicado: (2018)

Gene Expression Profiles in Primary Sjögren's Syndrome With and Without Systemic Manifestations
por: Vitali, Claudio, et al.
Publicado: (2019)

Profibrotic Effects of Endothelin-1 on Fibroblasts Are Mediated by Aldosterone In Vitro: Relevance to the Pathogenesis and Therapy of Systemic Sclerosis and Pulmonary Arterial Hypertension
por: Argentino, Giuseppe, et al.
Publicado: (2022)

In Type 1 Diabetes a Subset of Anti-Coxsackievirus B4 Antibodies Recognize Autoantigens and Induce Apoptosis of Pancreatic Beta Cells
por: Bason, Caterina, et al.
Publicado: (2013)

Immune Response to Rotavirus and Gluten Sensitivity
por: Puccetti, Antonio, et al.
Publicado: (2018)

In Celiac Disease, a Subset of Autoantibodies against Transglutaminase Binds Toll-Like Receptor 4 and Induces Activation of Monocytes
por: Zanoni, Giovanna, et al.
Publicado: (2006)

DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models
por: Zhang, Zongwang, et al.
Publicado: (2019)

Elevated Circulatory Levels of Microparticles Are Associated to Lung Fibrosis and Vasculopathy During Systemic Sclerosis
por: Leleu, Damien, et al.
Publicado: (2020)

Plant-Derived Chimeric Virus Particles for the Diagnosis of Primary Sjögren Syndrome
por: Tinazzi, Elisa, et al.
Publicado: (2015)

Identification of a Novel Serological Marker in Seronegative Rheumatoid Arthritis Using the Peptide Library Approach
por: Bason, Caterina, et al.
Publicado: (2021)

Dermoscopic features of livedoid vasculopathy
por: Hu, Stephen Chu-Sung, et al.
Publicado: (2017)

The Many Faces of Interleukin-6: The Role of IL-6 in Inflammation, Vasculopathy, and Fibrosis in Systemic Sclerosis
por: Barnes, Theresa C., et al.
Publicado: (2011)

Proposition of a novel animal model of systemic sclerosis induced by type V collagen in C57BL/6 mice that reproduces fibrosis, vasculopathy and autoimmunity
por: Teodoro, Walcy Rosolia, et al.
Publicado: (2019)

Fibrosis in systemic sclerosis: common and unique pathobiology
por: Bhattacharyya, Swati, et al.
Publicado: (2012)

Clinical and dermoscopic features of livedoid vasculopathy
por: Wen, Juan, et al.
Publicado: (2020)

Bar code reader – an algorithmic approach to cutaneous occluding vasculopathies? Part I: small vessel vasculopathies
por: Ratzinger, Gudrun, et al.
Publicado: (2019)

Bar Code Reader – an algorithmic approach to cutaneous occluding vasculopathies? part II medium vessel vasculopathies
por: Ratzinger, Gudrun, et al.
Publicado: (2019)

GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
por: López-Isac, Elena, et al.
Publicado: (2019)

The Role of Oxidative Stress in the Development of Systemic Sclerosis Related Vasculopathy
por: Abdulle, Amaal E., et al.
Publicado: (2018)

Downregulation of Vascular Hemeoxygenase-1 Leads to Vasculopathy in Systemic Sclerosis
por: Ross, Rebecca L, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h5b09571d9dppjvkr4p085csru