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Daylight Saving Time and Acute Myocardial Infarction: A Meta-Analysis

Background: The available evidence on the effects of daylight saving time (DST) transitions on major cardiovascular diseases is limited and conflicting. We carried out the first meta-analysis aimed at evaluating the risk of acute myocardial infarction (AMI) following DST transitions. Methods: We sea...

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Autores principales: Manfredini, Roberto, Fabbian, Fabio, Cappadona, Rosaria, De Giorgi, Alfredo, Bravi, Francesca, Carradori, Tiziano, Flacco, Maria Elena, Manzoli, Lamberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463000/
https://www.ncbi.nlm.nih.gov/pubmed/30909587
http://dx.doi.org/10.3390/jcm8030404
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author Manfredini, Roberto
Fabbian, Fabio
Cappadona, Rosaria
De Giorgi, Alfredo
Bravi, Francesca
Carradori, Tiziano
Flacco, Maria Elena
Manzoli, Lamberto
author_facet Manfredini, Roberto
Fabbian, Fabio
Cappadona, Rosaria
De Giorgi, Alfredo
Bravi, Francesca
Carradori, Tiziano
Flacco, Maria Elena
Manzoli, Lamberto
author_sort Manfredini, Roberto
collection PubMed
description Background: The available evidence on the effects of daylight saving time (DST) transitions on major cardiovascular diseases is limited and conflicting. We carried out the first meta-analysis aimed at evaluating the risk of acute myocardial infarction (AMI) following DST transitions. Methods: We searched cohort or case-control studies evaluating the incidence of AMI, among adults (≥18 y), during the weeks following spring and/or autumn DST shifts, versus control periods. The search was made in MedLine and Scopus, up to 31 December 2018, with no language restriction. A summary odds ratio of AMI was computed after: (1) spring, (2) autumn or (3) both transitions considered together. Meta-analyses were also stratified by gender and age. Data were combined using a generic inverse-variance approach. Results: Seven studies (>115,000 subjects) were included in the analyses. A significantly higher risk of AMI (Odds Ratio: 1.03; 95% CI: 1.01–1.06) was observed during the two weeks following spring or autumn DST transitions. However, although AMI risk increased significantly after the spring shift (OR: 1.05; 1.02–1.07), the incidence of AMI during the week after winter DST transition was comparable with control periods (OR 1.01; 0.98–1.04). No substantial differences were observed when the analyses were stratified by age or gender. Conclusion: The risk of AMI increases modestly but significantly after DST transitions, supporting the proposal of DST shifts discontinuation. Additional studies that fully adjust for potential confounders are required to confirm the present findings.
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spelling pubmed-64630002019-04-19 Daylight Saving Time and Acute Myocardial Infarction: A Meta-Analysis Manfredini, Roberto Fabbian, Fabio Cappadona, Rosaria De Giorgi, Alfredo Bravi, Francesca Carradori, Tiziano Flacco, Maria Elena Manzoli, Lamberto J Clin Med Review Background: The available evidence on the effects of daylight saving time (DST) transitions on major cardiovascular diseases is limited and conflicting. We carried out the first meta-analysis aimed at evaluating the risk of acute myocardial infarction (AMI) following DST transitions. Methods: We searched cohort or case-control studies evaluating the incidence of AMI, among adults (≥18 y), during the weeks following spring and/or autumn DST shifts, versus control periods. The search was made in MedLine and Scopus, up to 31 December 2018, with no language restriction. A summary odds ratio of AMI was computed after: (1) spring, (2) autumn or (3) both transitions considered together. Meta-analyses were also stratified by gender and age. Data were combined using a generic inverse-variance approach. Results: Seven studies (>115,000 subjects) were included in the analyses. A significantly higher risk of AMI (Odds Ratio: 1.03; 95% CI: 1.01–1.06) was observed during the two weeks following spring or autumn DST transitions. However, although AMI risk increased significantly after the spring shift (OR: 1.05; 1.02–1.07), the incidence of AMI during the week after winter DST transition was comparable with control periods (OR 1.01; 0.98–1.04). No substantial differences were observed when the analyses were stratified by age or gender. Conclusion: The risk of AMI increases modestly but significantly after DST transitions, supporting the proposal of DST shifts discontinuation. Additional studies that fully adjust for potential confounders are required to confirm the present findings. MDPI 2019-03-23 /pmc/articles/PMC6463000/ /pubmed/30909587 http://dx.doi.org/10.3390/jcm8030404 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Manfredini, Roberto
Fabbian, Fabio
Cappadona, Rosaria
De Giorgi, Alfredo
Bravi, Francesca
Carradori, Tiziano
Flacco, Maria Elena
Manzoli, Lamberto
Daylight Saving Time and Acute Myocardial Infarction: A Meta-Analysis
title Daylight Saving Time and Acute Myocardial Infarction: A Meta-Analysis
title_full Daylight Saving Time and Acute Myocardial Infarction: A Meta-Analysis
title_fullStr Daylight Saving Time and Acute Myocardial Infarction: A Meta-Analysis
title_full_unstemmed Daylight Saving Time and Acute Myocardial Infarction: A Meta-Analysis
title_short Daylight Saving Time and Acute Myocardial Infarction: A Meta-Analysis
title_sort daylight saving time and acute myocardial infarction: a meta-analysis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463000/
https://www.ncbi.nlm.nih.gov/pubmed/30909587
http://dx.doi.org/10.3390/jcm8030404
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