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Adult Patient Risk Stratification Using a Risk Score for Periodontitis

Background: There is a need for analytical tools predicting the risk of periodontitis. The purpose of this study was to estimate and evaluate a risk score for prediction of periodontitis. Materials and methods: This case-cohort study included a random sample of 155 cases (with periodontitis) and 175...

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Autores principales: de Araújo Nobre, Miguel, Ferro, Ana, Maló, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463020/
https://www.ncbi.nlm.nih.gov/pubmed/30841500
http://dx.doi.org/10.3390/jcm8030307
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author de Araújo Nobre, Miguel
Ferro, Ana
Maló, Paulo
author_facet de Araújo Nobre, Miguel
Ferro, Ana
Maló, Paulo
author_sort de Araújo Nobre, Miguel
collection PubMed
description Background: There is a need for analytical tools predicting the risk of periodontitis. The purpose of this study was to estimate and evaluate a risk score for prediction of periodontitis. Materials and methods: This case-cohort study included a random sample of 155 cases (with periodontitis) and 175 controls (randomly sampled from the study population at baseline) that were followed for 3-year. A logistic regression model was used with estimation of the risk ratio (RR) for each potential predictor. Results: The risk model included the predictors “age > 53 years” (RR = 0.53), “smoking” (RR = 2.9), “gingivitis at baseline” (RR = 3.1), “subgingival calculus at baseline” (RR = 1.9), “history of periodontitis” (RR = 2.3), and “less than 2 observations in the first year of follow-up” (RR = 3.7). Patients were distributed into three risk groups based on the preanalysis risk: low risk, moderate risk, and high risk. The risk score discrimination (95% confidence interval (CI)) was 0.75 (0.70; 0.80) (p < 0.001, C-statistic). Conclusions: The risk score estimated in the present study enabled to identify patients at higher risk of experiencing periodontitis and may be considered a useful tool for both clinicians and patients.
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spelling pubmed-64630202019-04-19 Adult Patient Risk Stratification Using a Risk Score for Periodontitis de Araújo Nobre, Miguel Ferro, Ana Maló, Paulo J Clin Med Article Background: There is a need for analytical tools predicting the risk of periodontitis. The purpose of this study was to estimate and evaluate a risk score for prediction of periodontitis. Materials and methods: This case-cohort study included a random sample of 155 cases (with periodontitis) and 175 controls (randomly sampled from the study population at baseline) that were followed for 3-year. A logistic regression model was used with estimation of the risk ratio (RR) for each potential predictor. Results: The risk model included the predictors “age > 53 years” (RR = 0.53), “smoking” (RR = 2.9), “gingivitis at baseline” (RR = 3.1), “subgingival calculus at baseline” (RR = 1.9), “history of periodontitis” (RR = 2.3), and “less than 2 observations in the first year of follow-up” (RR = 3.7). Patients were distributed into three risk groups based on the preanalysis risk: low risk, moderate risk, and high risk. The risk score discrimination (95% confidence interval (CI)) was 0.75 (0.70; 0.80) (p < 0.001, C-statistic). Conclusions: The risk score estimated in the present study enabled to identify patients at higher risk of experiencing periodontitis and may be considered a useful tool for both clinicians and patients. MDPI 2019-03-05 /pmc/articles/PMC6463020/ /pubmed/30841500 http://dx.doi.org/10.3390/jcm8030307 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de Araújo Nobre, Miguel
Ferro, Ana
Maló, Paulo
Adult Patient Risk Stratification Using a Risk Score for Periodontitis
title Adult Patient Risk Stratification Using a Risk Score for Periodontitis
title_full Adult Patient Risk Stratification Using a Risk Score for Periodontitis
title_fullStr Adult Patient Risk Stratification Using a Risk Score for Periodontitis
title_full_unstemmed Adult Patient Risk Stratification Using a Risk Score for Periodontitis
title_short Adult Patient Risk Stratification Using a Risk Score for Periodontitis
title_sort adult patient risk stratification using a risk score for periodontitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463020/
https://www.ncbi.nlm.nih.gov/pubmed/30841500
http://dx.doi.org/10.3390/jcm8030307
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