Defective Phosphatidylglycerol Remodeling Causes Hepatopathy, Linking Mitochondrial Dysfunction to Hepatosteatosis

BACKGROUND & AIMS: Obesity promotes the development of nonalcoholic fatty liver diseases (NAFLDs), yet not all obese patients develop NAFLD. The underlying causes for this discrepancy remain elusive. LPGAT1 is an acyltransferase that catalyzes the remodeling of phosphatidylglycerol (PG), a mitoc...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyang, Zhang, Jun, Sun, Haoran, Liu, Xueling, Zheng, Yue, Xu, Dan, Wang, Jianing, Jia, Dandan, Han, Xianlin, Liu, Feng, Nie, Jia, Shi, Yuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463126/
https://www.ncbi.nlm.nih.gov/pubmed/30831319
http://dx.doi.org/10.1016/j.jcmgh.2019.02.002

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