Cargando…
MmpL Proteins in Physiology and Pathogenesis of M. tuberculosis
Mycobacterium tuberculosis (Mtb) remains an important human pathogen. The Mtb cell envelope is a critical bacterial structure that contributes to virulence and pathogenicity. Mycobacterial membrane protein large (MmpL) proteins export bulky, hydrophobic substrates that are essential for the unique s...
Autores principales: | Melly, Geoff, Purdy, Georgiana E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463170/ https://www.ncbi.nlm.nih.gov/pubmed/30841535 http://dx.doi.org/10.3390/microorganisms7030070 |
Ejemplares similares
-
Multiple Mutations in Mycobacterium tuberculosis MmpL3 Increase Resistance to MmpL3 Inhibitors
por: McNeil, Matthew B., et al.
Publicado: (2020) -
Resistance against Membrane-Inserting MmpL3 Inhibitor through Upregulation of MmpL5 in Mycobacterium tuberculosis
por: Li, Ming, et al.
Publicado: (2020) -
Targeting MmpL3 for anti-tuberculosis drug development
por: Bolla, Jani R.
Publicado: (2020) -
Two-Way Regulation of MmpL3 Expression Identifies
and Validates Inhibitors of MmpL3 Function in Mycobacterium
tuberculosis
por: Grover, Shipra, et al.
Publicado: (2020) -
Coexpression of MmpS5 and MmpL5 Contributes to Both Efflux Transporter MmpL5 Trimerization and Drug Resistance in Mycobacterium tuberculosis
por: Yamamoto, Kentaro, et al.
Publicado: (2021)