Dynamical Task Switching in Cellular Computers

We present a scheme for implementing a version of task switching in engineered bacteria, based on the manipulation of plasmid copy numbers. Our method allows for the embedding of multiple computations in a cellular population, whilst minimising resource usage inefficiency. We describe the results of...

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Detalles Bibliográficos
Autores principales: Goñi-Moreno, Angel, de la Cruz, Fernando, Rodríguez-Patón, Alfonso, Amos, Martyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463194/
https://www.ncbi.nlm.nih.gov/pubmed/30691149
http://dx.doi.org/10.3390/life9010014
Descripción
Sumario:We present a scheme for implementing a version of task switching in engineered bacteria, based on the manipulation of plasmid copy numbers. Our method allows for the embedding of multiple computations in a cellular population, whilst minimising resource usage inefficiency. We describe the results of computational simulations of our model, and discuss the potential for future work in this area.

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