Dynamical Task Switching in Cellular Computers

We present a scheme for implementing a version of task switching in engineered bacteria, based on the manipulation of plasmid copy numbers. Our method allows for the embedding of multiple computations in a cellular population, whilst minimising resource usage inefficiency. We describe the results of...

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Detalles Bibliográficos
Autores principales: Goñi-Moreno, Angel, de la Cruz, Fernando, Rodríguez-Patón, Alfonso, Amos, Martyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463194/
https://www.ncbi.nlm.nih.gov/pubmed/30691149
http://dx.doi.org/10.3390/life9010014
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author Goñi-Moreno, Angel
de la Cruz, Fernando
Rodríguez-Patón, Alfonso
Amos, Martyn
author_facet Goñi-Moreno, Angel
de la Cruz, Fernando
Rodríguez-Patón, Alfonso
Amos, Martyn
author_sort Goñi-Moreno, Angel
collection PubMed
description We present a scheme for implementing a version of task switching in engineered bacteria, based on the manipulation of plasmid copy numbers. Our method allows for the embedding of multiple computations in a cellular population, whilst minimising resource usage inefficiency. We describe the results of computational simulations of our model, and discuss the potential for future work in this area.
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spelling pubmed-64631942019-04-22 Dynamical Task Switching in Cellular Computers Goñi-Moreno, Angel de la Cruz, Fernando Rodríguez-Patón, Alfonso Amos, Martyn Life (Basel) Article We present a scheme for implementing a version of task switching in engineered bacteria, based on the manipulation of plasmid copy numbers. Our method allows for the embedding of multiple computations in a cellular population, whilst minimising resource usage inefficiency. We describe the results of computational simulations of our model, and discuss the potential for future work in this area. MDPI 2019-01-26 /pmc/articles/PMC6463194/ /pubmed/30691149 http://dx.doi.org/10.3390/life9010014 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Goñi-Moreno, Angel
de la Cruz, Fernando
Rodríguez-Patón, Alfonso
Amos, Martyn
Dynamical Task Switching in Cellular Computers
title Dynamical Task Switching in Cellular Computers
title_full Dynamical Task Switching in Cellular Computers
title_fullStr Dynamical Task Switching in Cellular Computers
title_full_unstemmed Dynamical Task Switching in Cellular Computers
title_short Dynamical Task Switching in Cellular Computers
title_sort dynamical task switching in cellular computers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463194/
https://www.ncbi.nlm.nih.gov/pubmed/30691149
http://dx.doi.org/10.3390/life9010014
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AT delacruzfernando dynamicaltaskswitchingincellularcomputers
AT rodriguezpatonalfonso dynamicaltaskswitchingincellularcomputers
AT amosmartyn dynamicaltaskswitchingincellularcomputers

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