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APOE-ε4 risk variant for Alzheimer's disease modifies the association between cognitive performance and cerebral morphology in healthy middle-aged individuals

The APOE-ε4 genotype is the highest genetic risk factor for Alzheimer's disease (AD). In cognitively unimpaired individuals, it has been related to altered brain morphology, function and earlier amyloid beta accumulation. However, its impact on cognitive performance is less evident. Here, we ex...

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Detalles Bibliográficos
Autores principales:	Cacciaglia, Raffaele, Molinuevo, José Luis, Falcón, Carles, Sánchez-Benavides, Gonzalo, Gramunt, Nina, Brugulat-Serrat, Anna, Esteller, Manel, Morán, Sebastián, Fauria, Karine, Gispert, Juan Domingo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463204/ https://www.ncbi.nlm.nih.gov/pubmed/30991302 http://dx.doi.org/10.1016/j.nicl.2019.101818

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