[(18)F]Amylovis as a Potential PET Probe for β-Amyloid Plaque: Synthesis, In Silico, In vitro and In vivo Evaluations

BACKGROUND: Alzheimer’s disease (AD) is the most common form of dementia. Neuroimaging methods have widened the horizons for AD diagnosis and therapy. The goals of this work are the synthesis of 2-(3-fluoropropyl)-6-methoxynaphthalene (5) and its [(18)F]-radiolabeled counterpart ([(18)F]Amylovis), t...

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Detalles Bibliográficos
Autores principales: Rivera-Marrero, Suchitil, Fernández-Maza, Laura, León-Chaviano, Samila, Sablón-Carrazana, Marquiza, Bencomo-Martínez, Alberto, Perera-Pintado, Alejandro, Prats-Capote, Anais, Zoppolo, Florencia, Kreimerman, Ingrid, Pardo, Tania, Reyes, Laura, Balcerzyk, Marcin, Dubed-Bandomo, Geyla, Mercerón-Martínez, Daymara, Espinosa-Rodríguez, Luis A., Engler, Henry, Savio, Eduardo, Rodríguez-Tanty, Chryslaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463402/
https://www.ncbi.nlm.nih.gov/pubmed/30605068
http://dx.doi.org/10.2174/1874471012666190102165053

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