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Sleep in Offspring of Parents With Mood Disorders

Background: Sleep problems in childhood are an early predictor of mood disorders among individuals at high familial risk. However, the majority of the research has focused on sleep disturbances in already diagnosed individuals and has largely neglected investigating potential differences between wee...

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Autores principales: Wescott, Delainey L., Morash-Conway, Jessica, Zwicker, Alyson, Cumby, Jill, Uher, Rudolf, Rusak, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463540/
https://www.ncbi.nlm.nih.gov/pubmed/31024367
http://dx.doi.org/10.3389/fpsyt.2019.00225
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author Wescott, Delainey L.
Morash-Conway, Jessica
Zwicker, Alyson
Cumby, Jill
Uher, Rudolf
Rusak, Benjamin
author_facet Wescott, Delainey L.
Morash-Conway, Jessica
Zwicker, Alyson
Cumby, Jill
Uher, Rudolf
Rusak, Benjamin
author_sort Wescott, Delainey L.
collection PubMed
description Background: Sleep problems in childhood are an early predictor of mood disorders among individuals at high familial risk. However, the majority of the research has focused on sleep disturbances in already diagnosed individuals and has largely neglected investigating potential differences between weeknight and weekend sleep in high-risk offspring. This study examined sleep parameters in offspring of parents with major depressive disorder or bipolar disorder during both weeknights and weekends. Methods: We used actigraphy, sleep diaries, and questionnaires to measure several sleep characteristics in 73 offspring aged 4–19 years: 23 offspring of a parent with major depressive disorder, 22 offspring of a parent with bipolar disorder, and 28 control offspring. Results: Offspring of parents with major depressive disorder slept, on average, 26 min more than control offspring on weeknights (95% confidence interval, 3 to 49 min, p = 0.027). Offspring of parents with bipolar disorder slept, on average, 27 min more on weekends than on weeknights compared to controls, resulting in a significant family history × weekend interaction (95% confidence interval, 7 to 47 min, p = 0.008). Conclusions: Sleep patterns in children and adolescents were related to the psychiatric diagnosis of their parent(s). Future follow-up of these results may clarify the relations between early sleep differences and the risk of developing mood disorders in individuals at high familial risk.
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spelling pubmed-64635402019-04-25 Sleep in Offspring of Parents With Mood Disorders Wescott, Delainey L. Morash-Conway, Jessica Zwicker, Alyson Cumby, Jill Uher, Rudolf Rusak, Benjamin Front Psychiatry Psychiatry Background: Sleep problems in childhood are an early predictor of mood disorders among individuals at high familial risk. However, the majority of the research has focused on sleep disturbances in already diagnosed individuals and has largely neglected investigating potential differences between weeknight and weekend sleep in high-risk offspring. This study examined sleep parameters in offspring of parents with major depressive disorder or bipolar disorder during both weeknights and weekends. Methods: We used actigraphy, sleep diaries, and questionnaires to measure several sleep characteristics in 73 offspring aged 4–19 years: 23 offspring of a parent with major depressive disorder, 22 offspring of a parent with bipolar disorder, and 28 control offspring. Results: Offspring of parents with major depressive disorder slept, on average, 26 min more than control offspring on weeknights (95% confidence interval, 3 to 49 min, p = 0.027). Offspring of parents with bipolar disorder slept, on average, 27 min more on weekends than on weeknights compared to controls, resulting in a significant family history × weekend interaction (95% confidence interval, 7 to 47 min, p = 0.008). Conclusions: Sleep patterns in children and adolescents were related to the psychiatric diagnosis of their parent(s). Future follow-up of these results may clarify the relations between early sleep differences and the risk of developing mood disorders in individuals at high familial risk. Frontiers Media S.A. 2019-04-08 /pmc/articles/PMC6463540/ /pubmed/31024367 http://dx.doi.org/10.3389/fpsyt.2019.00225 Text en Copyright © 2019 Wescott, Morash-Conway, Zwicker, Cumby, Uher and Rusak http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Wescott, Delainey L.
Morash-Conway, Jessica
Zwicker, Alyson
Cumby, Jill
Uher, Rudolf
Rusak, Benjamin
Sleep in Offspring of Parents With Mood Disorders
title Sleep in Offspring of Parents With Mood Disorders
title_full Sleep in Offspring of Parents With Mood Disorders
title_fullStr Sleep in Offspring of Parents With Mood Disorders
title_full_unstemmed Sleep in Offspring of Parents With Mood Disorders
title_short Sleep in Offspring of Parents With Mood Disorders
title_sort sleep in offspring of parents with mood disorders
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463540/
https://www.ncbi.nlm.nih.gov/pubmed/31024367
http://dx.doi.org/10.3389/fpsyt.2019.00225
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