Melittin Inhibits Hypoxia-Induced Vasculogenic Mimicry Formation and Epithelial-Mesenchymal Transition through Suppression of HIF-1α/Akt Pathway in Liver Cancer

In this study, we investigated whether melittin could suppress hypoxia-induced vasculogenic mimicry (VM) formation in liver cancer and explored the underlying mechanisms. Melittin significantly inhibited the proliferation of liver cancer cells with or without CoCl(2) presence. Melittin also signific...

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Detalles Bibliográficos
Autores principales: Chen, Qunwei, Lin, Wanfu, Yin, Zifei, Zou, Yong, Liang, Shufang, Ruan, Shanming, Chen, Peifeng, Li, Shu, Shu, Qijin, Cheng, Binbin, Ling, Changquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463627/
https://www.ncbi.nlm.nih.gov/pubmed/31057657
http://dx.doi.org/10.1155/2019/9602935

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