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Chimeric Antigen Receptor T Cell Bearing Herpes Virus Entry Mediator Co-stimulatory Signal Domain Exhibits High Functional Potency

Chimeric antigen receptor (CAR) is a hybrid molecule consisting of an antigen-binding domain and a signal transduction domain. The artificial T cells expressing CAR (CAR-T cells) are expected to be a useful tool for treatment of various diseases, such as cancer. The addition of a co-stimulatory sign...

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Detalles Bibliográficos
Autores principales:	Nunoya, Jun-ichi, Masuda, Michiaki, Ye, Chaobaihui, Su, Lishan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463745/ https://www.ncbi.nlm.nih.gov/pubmed/31011630 http://dx.doi.org/10.1016/j.omto.2019.03.002

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