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Minimally Invasive Laser Treatment of Ureterocele

Introduction: Ureterocelemay cause severe pyelo-ureteral obstruction with afebrile urinary tract infections in infants and children. Early decompressive treatment is advocated to reduce the risk of related renal and urinary tract damage. Endoscopic techniques of incision have been offered utilizing...

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Autores principales: Caione, Paolo, Gerocarni Nappo, Simona, Collura, Giuseppe, Matarazzo, Ennio, Bada, Maida, Del Prete, Laura, Innocenzi, Michele, Mele, Ermelinda, Capozza, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463783/
https://www.ncbi.nlm.nih.gov/pubmed/31024867
http://dx.doi.org/10.3389/fped.2019.00106
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author Caione, Paolo
Gerocarni Nappo, Simona
Collura, Giuseppe
Matarazzo, Ennio
Bada, Maida
Del Prete, Laura
Innocenzi, Michele
Mele, Ermelinda
Capozza, Nicola
author_facet Caione, Paolo
Gerocarni Nappo, Simona
Collura, Giuseppe
Matarazzo, Ennio
Bada, Maida
Del Prete, Laura
Innocenzi, Michele
Mele, Ermelinda
Capozza, Nicola
author_sort Caione, Paolo
collection PubMed
description Introduction: Ureterocelemay cause severe pyelo-ureteral obstruction with afebrile urinary tract infections in infants and children. Early decompressive treatment is advocated to reduce the risk of related renal and urinary tract damage. Endoscopic techniques of incision have been offered utilizing diathermic electrode. We adopted laser energy to release the obstruction of the ureterocele and reduce the need of further surgery. Our technique is described and results are presented, compared with a group of matched patients treated by diathermic energy. Materials and methods: Decompression was performed by endoscopic multiple punctures at the basis of the ureterocele. Holmium YAG Laser was utilized with 0.5–0.8 joule energy, through 8–9.8F cystoscope under general anesthesia. The control group received ureterocele incision by diathermic energy through pediatric resettoscope. Foley indwelling catheter was removed after 18–24 h. Renal ultrasound was performed at 1, 3, 6, and 12 months follow-up. Voiding cysto-urethrogram and radionuclide renal scan were done at 6–18 months in selected cases. Statistical analysis was utilized for data evaluation. Results: From January 2012 to December 2017, 64 endoscopic procedures were performed: 49 were ectopic and 15 orthotopicureteroceles. Fifty-three were in duplex systems, mostly ectopic. Mean age at endoscopy was 6.3 months (1–168). Immediate decompression of the ureterocele was obtained, but in five cases (8%) a second endoscopic puncture was necessary at 6–18 months follow-up for recurrent dilatation. Urinary tract infections and de novo refluxes occurred in 23.4 and 29.7% in the study group, compared to 38.5 and 61.5% in the 26 controls (p < 0.05). Further surgery was required in 12 patients (18%) at 1–5 years follow-up (10 in ectopic ureteroceles with duplex systems): seven ureteral reimplantation for reflux, five laparoscopic hemy-nephro-ureterectomy. Orthotopic ureteroceceles had better outcome. Secondary surgery was necessary in 13 patients (50.0%) of control group (p < 0.05). Conclusions: Early endoscopic decompression should be considered first line treatment of obstructing ureterocele in infants and children. Multiple punctures at the basis of the ureterocele, performed by low laser energy, is resulted a really minimally invasive treatment, providing immediate decompression of the upper urinary tract, and reducing the risk of further aggressive surgery.
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spelling pubmed-64637832019-04-25 Minimally Invasive Laser Treatment of Ureterocele Caione, Paolo Gerocarni Nappo, Simona Collura, Giuseppe Matarazzo, Ennio Bada, Maida Del Prete, Laura Innocenzi, Michele Mele, Ermelinda Capozza, Nicola Front Pediatr Pediatrics Introduction: Ureterocelemay cause severe pyelo-ureteral obstruction with afebrile urinary tract infections in infants and children. Early decompressive treatment is advocated to reduce the risk of related renal and urinary tract damage. Endoscopic techniques of incision have been offered utilizing diathermic electrode. We adopted laser energy to release the obstruction of the ureterocele and reduce the need of further surgery. Our technique is described and results are presented, compared with a group of matched patients treated by diathermic energy. Materials and methods: Decompression was performed by endoscopic multiple punctures at the basis of the ureterocele. Holmium YAG Laser was utilized with 0.5–0.8 joule energy, through 8–9.8F cystoscope under general anesthesia. The control group received ureterocele incision by diathermic energy through pediatric resettoscope. Foley indwelling catheter was removed after 18–24 h. Renal ultrasound was performed at 1, 3, 6, and 12 months follow-up. Voiding cysto-urethrogram and radionuclide renal scan were done at 6–18 months in selected cases. Statistical analysis was utilized for data evaluation. Results: From January 2012 to December 2017, 64 endoscopic procedures were performed: 49 were ectopic and 15 orthotopicureteroceles. Fifty-three were in duplex systems, mostly ectopic. Mean age at endoscopy was 6.3 months (1–168). Immediate decompression of the ureterocele was obtained, but in five cases (8%) a second endoscopic puncture was necessary at 6–18 months follow-up for recurrent dilatation. Urinary tract infections and de novo refluxes occurred in 23.4 and 29.7% in the study group, compared to 38.5 and 61.5% in the 26 controls (p < 0.05). Further surgery was required in 12 patients (18%) at 1–5 years follow-up (10 in ectopic ureteroceles with duplex systems): seven ureteral reimplantation for reflux, five laparoscopic hemy-nephro-ureterectomy. Orthotopic ureteroceceles had better outcome. Secondary surgery was necessary in 13 patients (50.0%) of control group (p < 0.05). Conclusions: Early endoscopic decompression should be considered first line treatment of obstructing ureterocele in infants and children. Multiple punctures at the basis of the ureterocele, performed by low laser energy, is resulted a really minimally invasive treatment, providing immediate decompression of the upper urinary tract, and reducing the risk of further aggressive surgery. Frontiers Media S.A. 2019-04-08 /pmc/articles/PMC6463783/ /pubmed/31024867 http://dx.doi.org/10.3389/fped.2019.00106 Text en Copyright © 2019 Caione, Gerocarni Nappo, Collura, Matarazzo, Bada, Del Prete, Innocenzi, Mele and Capozza. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Caione, Paolo
Gerocarni Nappo, Simona
Collura, Giuseppe
Matarazzo, Ennio
Bada, Maida
Del Prete, Laura
Innocenzi, Michele
Mele, Ermelinda
Capozza, Nicola
Minimally Invasive Laser Treatment of Ureterocele
title Minimally Invasive Laser Treatment of Ureterocele
title_full Minimally Invasive Laser Treatment of Ureterocele
title_fullStr Minimally Invasive Laser Treatment of Ureterocele
title_full_unstemmed Minimally Invasive Laser Treatment of Ureterocele
title_short Minimally Invasive Laser Treatment of Ureterocele
title_sort minimally invasive laser treatment of ureterocele
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463783/
https://www.ncbi.nlm.nih.gov/pubmed/31024867
http://dx.doi.org/10.3389/fped.2019.00106
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