FcγR-TLR Cross-Talk Enhances TNF Production by Human Monocyte-Derived DCs via IRF5-Dependent Gene Transcription and Glycolytic Reprogramming

Antigen-presenting cells (APCs) such as dendritic cells (DCs) are crucial for initiation of adequate inflammatory responses, which critically depends on the cooperated engagement of different receptors. In addition to pattern recognition receptors (PRRs), Fc gamma receptors (FcγRs) have recently bee...

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Detalles Bibliográficos
Autores principales: Hoepel, Willianne, Newling, Melissa, Vogelpoel, Lisa T. C., Sritharan, Lathees, Hansen, Ivo S., Kapsenberg, Martien L., Baeten, Dominique L. P., Everts, Bart, den Dunnen, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464031/
https://www.ncbi.nlm.nih.gov/pubmed/31024565
http://dx.doi.org/10.3389/fimmu.2019.00739

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