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The Rate Stabilizing Tool: Generating Stable Local-Level Measures of Chronic Disease

Accurate and precise estimates of local-level epidemiologic measures are critical to informing policy and program decisions, but they often require advanced statistical knowledge, programming/coding skills, and extensive computing power. In response, we developed the Rate Stabilizing Tool (RST), an...

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Autores principales: Quick, Harrison, Tootoo, Joshua, Li, Ruiyang, Vaughan, Adam S., Schieb, Linda, Casper, Michele, Miranda, Marie Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464039/
https://www.ncbi.nlm.nih.gov/pubmed/30925140
http://dx.doi.org/10.5888/pcd16.180442
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author Quick, Harrison
Tootoo, Joshua
Li, Ruiyang
Vaughan, Adam S.
Schieb, Linda
Casper, Michele
Miranda, Marie Lynn
author_facet Quick, Harrison
Tootoo, Joshua
Li, Ruiyang
Vaughan, Adam S.
Schieb, Linda
Casper, Michele
Miranda, Marie Lynn
author_sort Quick, Harrison
collection PubMed
description Accurate and precise estimates of local-level epidemiologic measures are critical to informing policy and program decisions, but they often require advanced statistical knowledge, programming/coding skills, and extensive computing power. In response, we developed the Rate Stabilizing Tool (RST), an ArcGIS-based tool that enables users to input their own record-level data to generate more reliable age-standardized measures of chronic disease (eg, prevalence rates, mortality rates) or other population health outcomes at the county or census tract levels. The RST uses 2 forms of empirical Bayesian modeling (nonspatial and spatial) to estimate age-standardized rates and 95% credible intervals for user-specified geographic units. The RST also provides indicators of the reliability of point estimates. In addition to reviewing the RST’s statistical techniques, we present results from a simulation study that illustrates the key benefit of smoothing. We demonstrate the dramatic reduction in root mean-squared error (rMSE), indicating a better compromise between accuracy and stability for both smoothing approaches relative to the unsmoothed estimates. Finally, we provide an example of the RST’s use. This example uses heart disease mortality data for North Carolina census tracts to map the RST output, including reliability of estimates, and demonstrates a subsequent statistical test.
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spelling pubmed-64640392019-04-24 The Rate Stabilizing Tool: Generating Stable Local-Level Measures of Chronic Disease Quick, Harrison Tootoo, Joshua Li, Ruiyang Vaughan, Adam S. Schieb, Linda Casper, Michele Miranda, Marie Lynn Prev Chronic Dis Tools for Public Health Practice Accurate and precise estimates of local-level epidemiologic measures are critical to informing policy and program decisions, but they often require advanced statistical knowledge, programming/coding skills, and extensive computing power. In response, we developed the Rate Stabilizing Tool (RST), an ArcGIS-based tool that enables users to input their own record-level data to generate more reliable age-standardized measures of chronic disease (eg, prevalence rates, mortality rates) or other population health outcomes at the county or census tract levels. The RST uses 2 forms of empirical Bayesian modeling (nonspatial and spatial) to estimate age-standardized rates and 95% credible intervals for user-specified geographic units. The RST also provides indicators of the reliability of point estimates. In addition to reviewing the RST’s statistical techniques, we present results from a simulation study that illustrates the key benefit of smoothing. We demonstrate the dramatic reduction in root mean-squared error (rMSE), indicating a better compromise between accuracy and stability for both smoothing approaches relative to the unsmoothed estimates. Finally, we provide an example of the RST’s use. This example uses heart disease mortality data for North Carolina census tracts to map the RST output, including reliability of estimates, and demonstrates a subsequent statistical test. Centers for Disease Control and Prevention 2019-03-28 /pmc/articles/PMC6464039/ /pubmed/30925140 http://dx.doi.org/10.5888/pcd16.180442 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Tools for Public Health Practice
Quick, Harrison
Tootoo, Joshua
Li, Ruiyang
Vaughan, Adam S.
Schieb, Linda
Casper, Michele
Miranda, Marie Lynn
The Rate Stabilizing Tool: Generating Stable Local-Level Measures of Chronic Disease
title The Rate Stabilizing Tool: Generating Stable Local-Level Measures of Chronic Disease
title_full The Rate Stabilizing Tool: Generating Stable Local-Level Measures of Chronic Disease
title_fullStr The Rate Stabilizing Tool: Generating Stable Local-Level Measures of Chronic Disease
title_full_unstemmed The Rate Stabilizing Tool: Generating Stable Local-Level Measures of Chronic Disease
title_short The Rate Stabilizing Tool: Generating Stable Local-Level Measures of Chronic Disease
title_sort rate stabilizing tool: generating stable local-level measures of chronic disease
topic Tools for Public Health Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464039/
https://www.ncbi.nlm.nih.gov/pubmed/30925140
http://dx.doi.org/10.5888/pcd16.180442
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