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A network of human functional gene interactions from knockout fitness screens in cancer cells

Genetic interactions mediate the emergence of phenotype from genotype. The systematic survey of genetic interactions in yeast showed that genes operating in the same biological process have highly correlated genetic interaction profiles, and this observation has been exploited to infer gene function...

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Detalles Bibliográficos
Autores principales: Kim, Eiru, Dede, Merve, Lenoir, Walter F, Wang, Gang, Srinivasan, Sanjana, Colic, Medina, Hart, Traver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464042/
https://www.ncbi.nlm.nih.gov/pubmed/30979825
http://dx.doi.org/10.26508/lsa.201800278