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A network of human functional gene interactions from knockout fitness screens in cancer cells
Genetic interactions mediate the emergence of phenotype from genotype. The systematic survey of genetic interactions in yeast showed that genes operating in the same biological process have highly correlated genetic interaction profiles, and this observation has been exploited to infer gene function...
Autores principales: | Kim, Eiru, Dede, Merve, Lenoir, Walter F, Wang, Gang, Srinivasan, Sanjana, Colic, Medina, Hart, Traver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464042/ https://www.ncbi.nlm.nih.gov/pubmed/30979825 http://dx.doi.org/10.26508/lsa.201800278 |
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