DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169

Human Dual-specificity tyrosine (Y) Regulated Kinase 1A (DYRK1A) is encoded by a dosage dependent gene whereby either trisomy or haploinsufficiency result in developmental abnormalities. However, the function and regulation of this important protein kinase are not fully understood. Here, we report p...

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Detalles Bibliográficos
Autores principales: R. Menon, Vijay, Ananthapadmanabhan, Varsha, Swanson, Selene, Saini, Siddharth, Sesay, Fatmata, Yakovlev, Vasily, Florens, Laurence, DeCaprio, James A., P. Washburn, Michael, Dozmorov, Mikhail, Litovchick, Larisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464593/
https://www.ncbi.nlm.nih.gov/pubmed/30773093
http://dx.doi.org/10.1080/15384101.2019.1577525

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