Functional analysis of a frame-shift mutant of the dihydropyridine receptor pore subunit (α(1S)) expressing two complementary protein fragments

BACKGROUND: The L-type Ca(2+) channel formed by the dihydropyridine receptor (DHPR) of skeletal muscle senses the membrane voltage and opens the ryanodine receptor (RyR1). This channel-to-channel coupling is essential for Ca(2+) signaling but poorly understood. We characterized a single-base frame-s...

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Detalles Bibliográficos
Autores principales: Ahern, Chris A, Vallejo, Paola, Mortenson, Lindsay, Coronado, Roberto
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64647/
https://www.ncbi.nlm.nih.gov/pubmed/11806762

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