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Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases

The efficacy and safety of glecaprevir and pibrentasvir in Japanese patients with human immunodeficiency virus (HIV) and/or genotype 3 hepatitis C virus (HCV) infection is yet to be clarified. This is because no or only a few patients have been included in Japanese phase 3 trials. We herein report f...

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Autores principales: Sho, Takuya, Suda, Goki, Kimura, Megumi, Shimazaki, Tomoe, Maehara, Osamu, Shigesawa, Taku, Suzuki, Kazuharu, Nakamura, Akihisa, Ohara, Masatsugu, Umemura, Machiko, Izumi, Takaaki, Kawagishi, Naoki, Baba, Masaru, Nakai, Masato, Natsuizaka, Mitsuteru, Morikawa, Kenichi, Ogawa, Koji, Sakamoto, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465017/
https://www.ncbi.nlm.nih.gov/pubmed/30449808
http://dx.doi.org/10.2169/internalmedicine.1856-18
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author Sho, Takuya
Suda, Goki
Kimura, Megumi
Shimazaki, Tomoe
Maehara, Osamu
Shigesawa, Taku
Suzuki, Kazuharu
Nakamura, Akihisa
Ohara, Masatsugu
Umemura, Machiko
Izumi, Takaaki
Kawagishi, Naoki
Baba, Masaru
Nakai, Masato
Natsuizaka, Mitsuteru
Morikawa, Kenichi
Ogawa, Koji
Sakamoto, Naoya
author_facet Sho, Takuya
Suda, Goki
Kimura, Megumi
Shimazaki, Tomoe
Maehara, Osamu
Shigesawa, Taku
Suzuki, Kazuharu
Nakamura, Akihisa
Ohara, Masatsugu
Umemura, Machiko
Izumi, Takaaki
Kawagishi, Naoki
Baba, Masaru
Nakai, Masato
Natsuizaka, Mitsuteru
Morikawa, Kenichi
Ogawa, Koji
Sakamoto, Naoya
author_sort Sho, Takuya
collection PubMed
description The efficacy and safety of glecaprevir and pibrentasvir in Japanese patients with human immunodeficiency virus (HIV) and/or genotype 3 hepatitis C virus (HCV) infection is yet to be clarified. This is because no or only a few patients have been included in Japanese phase 3 trials. We herein report for the first time the successful treatment of glecaprevir and pibrentasvir in three Japanese patients with HIV and genotype 3 HCV coinfection as well as hemophilia. Glecaprevir and pibrentasvir treatment is safe and effective for Japanese patients with genotype 3 HCV and HIV coinfection.
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spelling pubmed-64650172019-04-16 Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases Sho, Takuya Suda, Goki Kimura, Megumi Shimazaki, Tomoe Maehara, Osamu Shigesawa, Taku Suzuki, Kazuharu Nakamura, Akihisa Ohara, Masatsugu Umemura, Machiko Izumi, Takaaki Kawagishi, Naoki Baba, Masaru Nakai, Masato Natsuizaka, Mitsuteru Morikawa, Kenichi Ogawa, Koji Sakamoto, Naoya Intern Med Case Report The efficacy and safety of glecaprevir and pibrentasvir in Japanese patients with human immunodeficiency virus (HIV) and/or genotype 3 hepatitis C virus (HCV) infection is yet to be clarified. This is because no or only a few patients have been included in Japanese phase 3 trials. We herein report for the first time the successful treatment of glecaprevir and pibrentasvir in three Japanese patients with HIV and genotype 3 HCV coinfection as well as hemophilia. Glecaprevir and pibrentasvir treatment is safe and effective for Japanese patients with genotype 3 HCV and HIV coinfection. The Japanese Society of Internal Medicine 2018-11-19 2019-03-15 /pmc/articles/PMC6465017/ /pubmed/30449808 http://dx.doi.org/10.2169/internalmedicine.1856-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Sho, Takuya
Suda, Goki
Kimura, Megumi
Shimazaki, Tomoe
Maehara, Osamu
Shigesawa, Taku
Suzuki, Kazuharu
Nakamura, Akihisa
Ohara, Masatsugu
Umemura, Machiko
Izumi, Takaaki
Kawagishi, Naoki
Baba, Masaru
Nakai, Masato
Natsuizaka, Mitsuteru
Morikawa, Kenichi
Ogawa, Koji
Sakamoto, Naoya
Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases
title Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases
title_full Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases
title_fullStr Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases
title_full_unstemmed Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases
title_short Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases
title_sort glecaprevir and pibrentasvir for japanese patients with human immunodeficiency virus and genotype 3 hepatitis c virus coinfection: a report of three cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465017/
https://www.ncbi.nlm.nih.gov/pubmed/30449808
http://dx.doi.org/10.2169/internalmedicine.1856-18
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