Cargando…
Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases
The efficacy and safety of glecaprevir and pibrentasvir in Japanese patients with human immunodeficiency virus (HIV) and/or genotype 3 hepatitis C virus (HCV) infection is yet to be clarified. This is because no or only a few patients have been included in Japanese phase 3 trials. We herein report f...
Autores principales: | , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465017/ https://www.ncbi.nlm.nih.gov/pubmed/30449808 http://dx.doi.org/10.2169/internalmedicine.1856-18 |
_version_ | 1783410886625460224 |
---|---|
author | Sho, Takuya Suda, Goki Kimura, Megumi Shimazaki, Tomoe Maehara, Osamu Shigesawa, Taku Suzuki, Kazuharu Nakamura, Akihisa Ohara, Masatsugu Umemura, Machiko Izumi, Takaaki Kawagishi, Naoki Baba, Masaru Nakai, Masato Natsuizaka, Mitsuteru Morikawa, Kenichi Ogawa, Koji Sakamoto, Naoya |
author_facet | Sho, Takuya Suda, Goki Kimura, Megumi Shimazaki, Tomoe Maehara, Osamu Shigesawa, Taku Suzuki, Kazuharu Nakamura, Akihisa Ohara, Masatsugu Umemura, Machiko Izumi, Takaaki Kawagishi, Naoki Baba, Masaru Nakai, Masato Natsuizaka, Mitsuteru Morikawa, Kenichi Ogawa, Koji Sakamoto, Naoya |
author_sort | Sho, Takuya |
collection | PubMed |
description | The efficacy and safety of glecaprevir and pibrentasvir in Japanese patients with human immunodeficiency virus (HIV) and/or genotype 3 hepatitis C virus (HCV) infection is yet to be clarified. This is because no or only a few patients have been included in Japanese phase 3 trials. We herein report for the first time the successful treatment of glecaprevir and pibrentasvir in three Japanese patients with HIV and genotype 3 HCV coinfection as well as hemophilia. Glecaprevir and pibrentasvir treatment is safe and effective for Japanese patients with genotype 3 HCV and HIV coinfection. |
format | Online Article Text |
id | pubmed-6465017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-64650172019-04-16 Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases Sho, Takuya Suda, Goki Kimura, Megumi Shimazaki, Tomoe Maehara, Osamu Shigesawa, Taku Suzuki, Kazuharu Nakamura, Akihisa Ohara, Masatsugu Umemura, Machiko Izumi, Takaaki Kawagishi, Naoki Baba, Masaru Nakai, Masato Natsuizaka, Mitsuteru Morikawa, Kenichi Ogawa, Koji Sakamoto, Naoya Intern Med Case Report The efficacy and safety of glecaprevir and pibrentasvir in Japanese patients with human immunodeficiency virus (HIV) and/or genotype 3 hepatitis C virus (HCV) infection is yet to be clarified. This is because no or only a few patients have been included in Japanese phase 3 trials. We herein report for the first time the successful treatment of glecaprevir and pibrentasvir in three Japanese patients with HIV and genotype 3 HCV coinfection as well as hemophilia. Glecaprevir and pibrentasvir treatment is safe and effective for Japanese patients with genotype 3 HCV and HIV coinfection. The Japanese Society of Internal Medicine 2018-11-19 2019-03-15 /pmc/articles/PMC6465017/ /pubmed/30449808 http://dx.doi.org/10.2169/internalmedicine.1856-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Sho, Takuya Suda, Goki Kimura, Megumi Shimazaki, Tomoe Maehara, Osamu Shigesawa, Taku Suzuki, Kazuharu Nakamura, Akihisa Ohara, Masatsugu Umemura, Machiko Izumi, Takaaki Kawagishi, Naoki Baba, Masaru Nakai, Masato Natsuizaka, Mitsuteru Morikawa, Kenichi Ogawa, Koji Sakamoto, Naoya Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases |
title | Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases |
title_full | Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases |
title_fullStr | Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases |
title_full_unstemmed | Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases |
title_short | Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases |
title_sort | glecaprevir and pibrentasvir for japanese patients with human immunodeficiency virus and genotype 3 hepatitis c virus coinfection: a report of three cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465017/ https://www.ncbi.nlm.nih.gov/pubmed/30449808 http://dx.doi.org/10.2169/internalmedicine.1856-18 |
work_keys_str_mv | AT shotakuya glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT sudagoki glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT kimuramegumi glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT shimazakitomoe glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT maeharaosamu glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT shigesawataku glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT suzukikazuharu glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT nakamuraakihisa glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT oharamasatsugu glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT umemuramachiko glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT izumitakaaki glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT kawagishinaoki glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT babamasaru glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT nakaimasato glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT natsuizakamitsuteru glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT morikawakenichi glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT ogawakoji glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT sakamotonaoya glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases AT glecaprevirandpibrentasvirforjapanesepatientswithhumanimmunodeficiencyvirusandgenotype3hepatitiscviruscoinfectionareportofthreecases |