Comprehensive analysis of Fc-mediated IgM binding to the Plasmodium falciparum erythrocyte membrane protein 1 family in three parasite clones

PfEMP1 is a family of adhesive proteins expressed on the surface of Plasmodium falciparum-infected erythrocytes (IEs), where they mediate adhesion of IEs to a range of host receptors. Efficient PfEMP1-dependent IE sequestration often depends on soluble serum proteins, including IgM. Here, we report...

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Detalles Bibliográficos
Autores principales: Quintana, Maria del Pilar, Ecklu-Mensah, Gertrude, Tcherniuk, Sergey O., Ditlev, Sisse Bolm, Oleinikov, Andrew V., Hviid, Lars, Lopez-Perez, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465264/
https://www.ncbi.nlm.nih.gov/pubmed/30988351
http://dx.doi.org/10.1038/s41598-019-42585-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465264/
https://www.ncbi.nlm.nih.gov/pubmed/30988351
http://dx.doi.org/10.1038/s41598-019-42585-0

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