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Sea snake cathelicidin (Hc-cath) exerts a protective effect in mouse models of lung inflammation and infection

We investigated the anti-inflammatory and antibacterial activities of Hc-cath, a cathelicidin peptide derived from the venom of the sea snake, Hydrophis cyanocyntus, using in vivo models of inflammation and infection. Hc-cath function was evaluated in in vitro, in vivo in the wax moth, Galleria mell...

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Detalles Bibliográficos
Autores principales: Carlile, Simon R., Shiels, Jenna, Kerrigan, Lauren, Delaney, Rebecca, Megaw, Julianne, Gilmore, Brendan F., Weldon, Sinéad, Dalton, John P., Taggart, Clifford C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465284/
https://www.ncbi.nlm.nih.gov/pubmed/30988402
http://dx.doi.org/10.1038/s41598-019-42537-8

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