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Centromere mechanical maturation during mammalian cell mitosis

During mitosis, tension develops across the centromere as a result of spindle-based forces. Metaphase tension may be critical in preventing mitotic chromosome segregation errors, however, the nature of force transmission at the centromere and the role of centromere mechanics in controlling metaphase...

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Detalles Bibliográficos
Autores principales: Harasymiw, Lauren A., Tank, Damien, McClellan, Mark, Panigrahy, Neha, Gardner, Melissa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465287/
https://www.ncbi.nlm.nih.gov/pubmed/30988289
http://dx.doi.org/10.1038/s41467-019-09578-z