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Reconstructing missing complex networks against adversarial interventions
Interactions within complex network components define their operational modes, collective behaviors and global functionality. Understanding the role of these interactions is limited by either sensing methodologies or intentional adversarial efforts that sabotage the network structure. To overcome th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465316/ https://www.ncbi.nlm.nih.gov/pubmed/30988308 http://dx.doi.org/10.1038/s41467-019-09774-x |
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author | Xue, Yuankun Bogdan, Paul |
author_facet | Xue, Yuankun Bogdan, Paul |
author_sort | Xue, Yuankun |
collection | PubMed |
description | Interactions within complex network components define their operational modes, collective behaviors and global functionality. Understanding the role of these interactions is limited by either sensing methodologies or intentional adversarial efforts that sabotage the network structure. To overcome the partial observability and infer with good fidelity the unobserved network structures (latent subnetworks that are not random samples of the full network), we propose a general causal inference framework for reconstructing network structures under unknown adversarial interventions. We explore its applicability in both biological and social systems to recover the latent structures of human protein complex interactions and brain connectomes, as well as to infer the camouflaged social network structure in a simulated removal process. The demonstrated effectiveness establishes its good potential for capturing hidden information in much broader research domains. |
format | Online Article Text |
id | pubmed-6465316 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-64653162019-04-17 Reconstructing missing complex networks against adversarial interventions Xue, Yuankun Bogdan, Paul Nat Commun Article Interactions within complex network components define their operational modes, collective behaviors and global functionality. Understanding the role of these interactions is limited by either sensing methodologies or intentional adversarial efforts that sabotage the network structure. To overcome the partial observability and infer with good fidelity the unobserved network structures (latent subnetworks that are not random samples of the full network), we propose a general causal inference framework for reconstructing network structures under unknown adversarial interventions. We explore its applicability in both biological and social systems to recover the latent structures of human protein complex interactions and brain connectomes, as well as to infer the camouflaged social network structure in a simulated removal process. The demonstrated effectiveness establishes its good potential for capturing hidden information in much broader research domains. Nature Publishing Group UK 2019-04-15 /pmc/articles/PMC6465316/ /pubmed/30988308 http://dx.doi.org/10.1038/s41467-019-09774-x Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Xue, Yuankun Bogdan, Paul Reconstructing missing complex networks against adversarial interventions |
title | Reconstructing missing complex networks against adversarial interventions |
title_full | Reconstructing missing complex networks against adversarial interventions |
title_fullStr | Reconstructing missing complex networks against adversarial interventions |
title_full_unstemmed | Reconstructing missing complex networks against adversarial interventions |
title_short | Reconstructing missing complex networks against adversarial interventions |
title_sort | reconstructing missing complex networks against adversarial interventions |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465316/ https://www.ncbi.nlm.nih.gov/pubmed/30988308 http://dx.doi.org/10.1038/s41467-019-09774-x |
work_keys_str_mv | AT xueyuankun reconstructingmissingcomplexnetworksagainstadversarialinterventions AT bogdanpaul reconstructingmissingcomplexnetworksagainstadversarialinterventions |