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Reconstructing missing complex networks against adversarial interventions

Interactions within complex network components define their operational modes, collective behaviors and global functionality. Understanding the role of these interactions is limited by either sensing methodologies or intentional adversarial efforts that sabotage the network structure. To overcome th...

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Detalles Bibliográficos
Autores principales: Xue, Yuankun, Bogdan, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465316/
https://www.ncbi.nlm.nih.gov/pubmed/30988308
http://dx.doi.org/10.1038/s41467-019-09774-x
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author Xue, Yuankun
Bogdan, Paul
author_facet Xue, Yuankun
Bogdan, Paul
author_sort Xue, Yuankun
collection PubMed
description Interactions within complex network components define their operational modes, collective behaviors and global functionality. Understanding the role of these interactions is limited by either sensing methodologies or intentional adversarial efforts that sabotage the network structure. To overcome the partial observability and infer with good fidelity the unobserved network structures (latent subnetworks that are not random samples of the full network), we propose a general causal inference framework for reconstructing network structures under unknown adversarial interventions. We explore its applicability in both biological and social systems to recover the latent structures of human protein complex interactions and brain connectomes, as well as to infer the camouflaged social network structure in a simulated removal process. The demonstrated effectiveness establishes its good potential for capturing hidden information in much broader research domains.
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spelling pubmed-64653162019-04-17 Reconstructing missing complex networks against adversarial interventions Xue, Yuankun Bogdan, Paul Nat Commun Article Interactions within complex network components define their operational modes, collective behaviors and global functionality. Understanding the role of these interactions is limited by either sensing methodologies or intentional adversarial efforts that sabotage the network structure. To overcome the partial observability and infer with good fidelity the unobserved network structures (latent subnetworks that are not random samples of the full network), we propose a general causal inference framework for reconstructing network structures under unknown adversarial interventions. We explore its applicability in both biological and social systems to recover the latent structures of human protein complex interactions and brain connectomes, as well as to infer the camouflaged social network structure in a simulated removal process. The demonstrated effectiveness establishes its good potential for capturing hidden information in much broader research domains. Nature Publishing Group UK 2019-04-15 /pmc/articles/PMC6465316/ /pubmed/30988308 http://dx.doi.org/10.1038/s41467-019-09774-x Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Xue, Yuankun
Bogdan, Paul
Reconstructing missing complex networks against adversarial interventions
title Reconstructing missing complex networks against adversarial interventions
title_full Reconstructing missing complex networks against adversarial interventions
title_fullStr Reconstructing missing complex networks against adversarial interventions
title_full_unstemmed Reconstructing missing complex networks against adversarial interventions
title_short Reconstructing missing complex networks against adversarial interventions
title_sort reconstructing missing complex networks against adversarial interventions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465316/
https://www.ncbi.nlm.nih.gov/pubmed/30988308
http://dx.doi.org/10.1038/s41467-019-09774-x
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