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Birth and Resuscitation of (p)ppGpp Induced Antibiotic Tolerant Persister Cells
Transient antibiotic treatment typically eradicates most sensitive bacteria except a few survivors called persisters. The second messenger (p)ppGpp plays a key role in persister formation in Escherichia coli populations but the underlying mechanisms have remained elusive. In this study we induced (p...
Autores principales: | Svenningsen, Mikkel Skjoldan, Veress, Alexandra, Harms, Alexander, Mitarai, Namiko, Semsey, Szabolcs |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465370/ https://www.ncbi.nlm.nih.gov/pubmed/30988388 http://dx.doi.org/10.1038/s41598-019-42403-7 |
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