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Absence of cytotoxic and inflammatory effects following in vitro exposure of chondrogenically-differentiated human mesenchymal stem cells to adenosine, lidocaine and Mg(2+) solution

BACKGROUND: ALM solution, a combination of adenosine, lidocaine and Mg(2+), is an emerging small volume therapy that has been shown to prevent and correct coagulopathy and surgery-related inflammation in preclinical models, though its application in orthopaedic surgery is yet to be demonstrated. The...

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Detalles Bibliográficos
Autores principales: McCutchan, Andrew, Dobson, Geoffrey P., Stewart, Natalie, Letson, Hayley L., Grant, Andrea L., Jovanovic, Ivana-Aleksandra, Hazratwala, Kaushik, Wilkinson, Matthew, McEwen, Peter, Morris, Jodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465392/
https://www.ncbi.nlm.nih.gov/pubmed/30989345
http://dx.doi.org/10.1186/s40634-019-0185-5