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The F1F3 Recombinant Chimera of Leishmania donovani-Nucleoside Hydrolase (NH36) and Its Epitopes Induce Cross-Protection Against Leishmania (V.) braziliensis Infection in Mice

Leishmania (V.) braziliensis is the etiological agent of Cutaneous (CL) and Mucocutaneous leishmaniasis (ML) in the New World. CL can be more benign but ML can be severe and disfiguring. Immunity to these diseases include hypersensitivity, an enhanced inflammatory response with strong IFN-γ and TNF-...

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Detalles Bibliográficos
Autores principales: Alves-Silva, Marcus Vinícius, Nico, Dirlei, de Luca, Paula Melo, Palatnik de-Sousa, Clarisa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465647/
https://www.ncbi.nlm.nih.gov/pubmed/31024556
http://dx.doi.org/10.3389/fimmu.2019.00724

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