Design, Synthesis, Antiviral Evaluation, and SAR Studies of New 1-(Phenylsulfonyl)-1H-Pyrazol−4-yl-Methylaniline Derivatives

A series of N-((3-phenyl-1-(phenylsulfonyl)-1H-pyrazol-4-yl)methyl)anilines 7a-p and 8a-l, structurally related to previously synthesized and tested (N-(1,3-diphenyl-1H-pyrazol-4-yl)methyl)anilines (1a-v), were designed and synthesized. The new derivatives were evaluated in cell-based assays for the...

Descripción completa

Detalles Bibliográficos
Autores principales: Desideri, Nicoletta, Fioravanti, Rossella, Proietti Monaco, Luca, Atzori, Elena Maria, Carta, Antonio, Delogu, Ilenia, Collu, Gabriella, Loddo, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465675/
https://www.ncbi.nlm.nih.gov/pubmed/31024899
http://dx.doi.org/10.3389/fchem.2019.00214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465675/
https://www.ncbi.nlm.nih.gov/pubmed/31024899
http://dx.doi.org/10.3389/fchem.2019.00214

Ejemplares similares