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Parameter Identification for a Model of Neonatal Fc Receptor-Mediated Recycling of Endogenous Immunoglobulin G in Humans

Salvage of endogenous immunoglobulin G (IgG) by the neonatal Fc receptor (FcRn) is implicated in many clinical areas, including therapeutic monoclonal antibody kinetics, patient monitoring in IgG multiple myeloma, and antibody-mediated transplant rejection. There is a clear clinical need for a fully...

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Detalles Bibliográficos
Autores principales:	Kendrick, Felicity, Evans, Neil D., Berlanga, Oscar, Harding, Stephen J., Chappell, Michael J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465738/ https://www.ncbi.nlm.nih.gov/pubmed/31024535 http://dx.doi.org/10.3389/fimmu.2019.00674

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