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Disrupted-in-Schizophrenia 1 (DISC1) Overexpression and Juvenile Immune Activation Cause Sex-Specific Schizophrenia-Related Psychopathology in Rats

Synaptic pruning is a critical refinement step during neurodevelopment, and schizophrenia has been associated with overpruning of cortical dendritic spines. Both human studies and animal models implicate disrupted-in-schizophrenia 1 (DISC1) gene as a strong susceptibility factor for schizophrenia. A...

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Detalles Bibliográficos
Autores principales:	Uzuneser, Taygun C., Speidel, Jil, Kogias, Georgios, Wang, An-Li, de Souza Silva, Maria A., Huston, Joseph P., Zoicas, Iulia, von Hörsten, Stephan, Kornhuber, Johannes, Korth, Carsten, Müller, Christian P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465888/ https://www.ncbi.nlm.nih.gov/pubmed/31057438 http://dx.doi.org/10.3389/fpsyt.2019.00222

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