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Epitope-Specific Serological Assays for RSV: Conformation Matters

Respiratory syncytial virus (RSV) causes substantial morbidity and mortality in children and older adults. An effective vaccine must elicit neutralizing antibodies targeting the RSV fusion (F) protein, which exists in two major conformations, pre-fusion (pre-F) and post-fusion (post-F). Although 50%...

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Detalles Bibliográficos
Autores principales:	Phung, Emily, Chang, Lauren A., Morabito, Kaitlyn M., Kanekiyo, Masaru, Chen, Man, Nair, Deepika, Kumar, Azad, Chen, Grace L., Ledgerwood, Julie E., Graham, Barney S., Ruckwardt, Tracy J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466065/ https://www.ncbi.nlm.nih.gov/pubmed/30813394 http://dx.doi.org/10.3390/vaccines7010023

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