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Mobile Microfluidics

Microfluidics platforms can program small amounts of fluids to execute a bio-protocol, and thus, can automate the work of a technician and also integrate a large part of laboratory equipment. Although most microfluidic systems have considerably reduced the size of a laboratory, they are still bencht...

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Detalles Bibliográficos
Autor principal: Alistar, Mirela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466190/
https://www.ncbi.nlm.nih.gov/pubmed/30609780
http://dx.doi.org/10.3390/bioengineering6010005
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author Alistar, Mirela
author_facet Alistar, Mirela
author_sort Alistar, Mirela
collection PubMed
description Microfluidics platforms can program small amounts of fluids to execute a bio-protocol, and thus, can automate the work of a technician and also integrate a large part of laboratory equipment. Although most microfluidic systems have considerably reduced the size of a laboratory, they are still benchtop units, of a size comparable to a desktop computer. In this paper, we argue that achieving true mobility in microfluidics would revolutionize the domain by making laboratory services accessible during traveling or even in daily situations, such as sport and outdoor activities. We review the existing efforts to achieve mobility in microfluidics, and we discuss the conditions mobile biochips need to satisfy. In particular, we show how we adapted an existing biochip for mobile use, and we present the results when using it during a train ride. Based on these results and our systematic discussion, we identify the challenges that need to be overcome at technical, usability and social levels. In analogy to the history of computing, we make some predictions on the future of mobile biochips. In our vision, mobile biochips will disrupt how people interact with a wide range of healthcare processes, including medical testing and synthesis of on-demand medicine.
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spelling pubmed-64661902019-04-19 Mobile Microfluidics Alistar, Mirela Bioengineering (Basel) Review Microfluidics platforms can program small amounts of fluids to execute a bio-protocol, and thus, can automate the work of a technician and also integrate a large part of laboratory equipment. Although most microfluidic systems have considerably reduced the size of a laboratory, they are still benchtop units, of a size comparable to a desktop computer. In this paper, we argue that achieving true mobility in microfluidics would revolutionize the domain by making laboratory services accessible during traveling or even in daily situations, such as sport and outdoor activities. We review the existing efforts to achieve mobility in microfluidics, and we discuss the conditions mobile biochips need to satisfy. In particular, we show how we adapted an existing biochip for mobile use, and we present the results when using it during a train ride. Based on these results and our systematic discussion, we identify the challenges that need to be overcome at technical, usability and social levels. In analogy to the history of computing, we make some predictions on the future of mobile biochips. In our vision, mobile biochips will disrupt how people interact with a wide range of healthcare processes, including medical testing and synthesis of on-demand medicine. MDPI 2019-01-03 /pmc/articles/PMC6466190/ /pubmed/30609780 http://dx.doi.org/10.3390/bioengineering6010005 Text en © 2019 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Alistar, Mirela
Mobile Microfluidics
title Mobile Microfluidics
title_full Mobile Microfluidics
title_fullStr Mobile Microfluidics
title_full_unstemmed Mobile Microfluidics
title_short Mobile Microfluidics
title_sort mobile microfluidics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466190/
https://www.ncbi.nlm.nih.gov/pubmed/30609780
http://dx.doi.org/10.3390/bioengineering6010005
work_keys_str_mv AT alistarmirela mobilemicrofluidics