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Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration
Increasing evidence suggests that neurodegenerative disorders share a common pathogenic feature: the presence of deposits of misfolded proteins with altered physicochemical properties in the Central Nervous System. Despite a lack of infectivity, experimental data show that the replication and propag...
Autores principales: | Scialò, Carlo, De Cecco, Elena, Manganotti, Paolo, Legname, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466326/ https://www.ncbi.nlm.nih.gov/pubmed/30875755 http://dx.doi.org/10.3390/v11030261 |
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