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Generation and Characterization of Anti-Filovirus Nucleoprotein Monoclonal Antibodies

Filoviruses cause lethal hemorrhagic fever in humans. The filovirus nucleoprotein (NP) is expressed in high abundance in infected cells and is essential for virus replication. To generate anti-filovirus monoclonal antibodies (mAbs) against the NP, mice were immunized with peptides known as B-cell ep...

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Detalles Bibliográficos
Autores principales: Rahim, Md Niaz, Wang, Min, Wang, Tong, He, Shihua, Griffin, Bryan D., Kobasa, Darwyn, Yang, Ruifu, Du, Zongmin, Qiu, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466340/
https://www.ncbi.nlm.nih.gov/pubmed/30875741
http://dx.doi.org/10.3390/v11030259

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