Restoration of mutant K-Ras repressed miR-199b inhibits K-Ras mutant non-small cell lung cancer progression

BACKGROUND: miRNAs play crucial role in the progression of K-Ras-mutated nonsmall cell lung cancer (NSCLC). However, most studies have focused on miRNAs that target K-Ras. Here, we investigated miRNAs regulated by mutant K-Ras and their functions. METHODS: miRNAs regulated by mutant K-Ras were scree...

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Detalles Bibliográficos
Autores principales: Jin, Hua, Jang, Yoonjeong, Cheng, Nian, Li, Qing, Cui, Peng-Fei, Zhou, Zhi-Wei, Jiang, Hu-Lin, Cho, Myung-Haing, Westover, Kenneth D., Tan, Qun-You, Xu, Cheng-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466664/
https://www.ncbi.nlm.nih.gov/pubmed/30987652
http://dx.doi.org/10.1186/s13046-019-1170-7

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