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Mouse germ line mutations due to retrotransposon insertions

Transposable element (TE) insertions are responsible for a significant fraction of spontaneous germ line mutations reported in inbred mouse strains. This major contribution of TEs to the mutational landscape in mouse contrasts with the situation in human, where their relative contribution as germ li...

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Detalles Bibliográficos
Autores principales: Gagnier, Liane, Belancio, Victoria P., Mager, Dixie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466679/
https://www.ncbi.nlm.nih.gov/pubmed/31011371
http://dx.doi.org/10.1186/s13100-019-0157-4